SCC3 Antibody

Datasheet

Code	CSB-PA963228XA01DOA
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Product Details
Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) SCC3 Polyclonal antibody

Uniprot No.

O82265

Target Names

SCC3

Alternative Names

SCC3 antibody; SA antibody; At2g47980 antibody; T9J23.3 antibody; Sister-chromatid cohesion protein 3 antibody; AtSCC3 antibody; Stromalin protein antibody

Raised in

Rabbit

Species Reactivity

Arabidopsis thaliana

Immunogen

Recombinant Arabidopsis thaliana SCC3 protein

Immunogen Species

Arabidopsis thaliana (Mouse-ear cress)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Customer Reviews and Q&A

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Target Background

Function

Essential component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. Required for centromere cohesion maintenance at anaphase I and for the monopolar orientation of the kinetochores during both male and female meiosis. Also involved in mitosis.

Gene References into Functions

REC8 and SCC3 are necessary not only to maintain centromere cohesion at anaphase I, but also for the monopolar orientation of the kinetochores during the first meiotic division [AtSCC3] PMID: 16176934

Subcellular Location

Nucleus. Chromosome. Note=In pollen mother cells (PMC), localized in nucleus from meiotic interphase up to and including metaphase I. During interphase, detected as foci in the nucleus. During leptotene and by zygotene and pachytene, localized in condensing chromosomes on chromatin, delineating the chromosome axis. At diplotene and diakinesis, remains on the chromosome axis at lower levels. At metaphase I, confined to the arms of each bivalent chromosomes. Excluded from centromeric regions.

Protein Families

SCC3 family

Tissue Specificity

Expressed in roots, mature leaves, buds and seedlings.

Database Links

KEGG: ath:AT2G47980

STRING: 3702.AT2G47980.1

UniGene: At.436

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Transmembrane Protein Questionnaire with Gifts

Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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