mau-2 Antibody

Code CSB-PA517706XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans mau-2 Polyclonal antibody
Uniprot No.
Target Names
mau-2
Alternative Names
mau-2 antibody; C09H6.3 antibody; Maternal uncoordinated protein 2 antibody; Cohesin loading complex subunit SCC4 homolog antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans mau-2 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Plays an important role in the loading of the cohesin complex on to DNA. Forms a heterodimeric complex (also known as cohesin loading complex) with scc-2/SCC2 which mediates the loading of the cohesin complex onto chromatin. Required for normal development until the fourth larval stage. Functions cell autonomously to guide migrations during the development of the nervous system. Participates in the guidance of mechanosensory neuron AVM by a slt-1-independent mechanism. Regulates chromosome segregation in early embryos.
Gene References into Functions
  1. mau-2 defines a novel guidance factor that might be involved in the intracellular processing of guidance cues encountered by migrating cells and axons during development PMID: 15539489
Subcellular Location
Nucleus, nucleoplasm. Cytoplasm. Note=Binds to chromatin from the end of mitosis until prophase. Localizes to the cytoplasm of neurons.
Protein Families
SCC4/mau-2 family
Database Links

KEGG: cel:CELE_C09H6.3

STRING: 6239.C09H6.3.1

UniGene: Cel.4960

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