sdc-1 Antibody

Code CSB-PA326136XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans sdc-1 Polyclonal antibody
Uniprot No.
Target Names
sdc-1
Alternative Names
sdc-1 antibody; egl-16 antibody; F52E10.1 antibody; Zinc finger protein sdc-1 antibody; Egg-laying defective protein 16 antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans sdc-1 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Embryonic transcription factor regulating downstream genes involved specifically in the sex determination and dosage compensation pathways, or regulating other genes involved in the coordinate control of both processes. Component of the SDC complex that functions in sex determination and in X chromosome dosage compensation specifically in hermaphrodite (XX) animals. Involved in the recruitment of the condensin I-like dosage compensation complex to the male sex-determining autosomal gene her-1, thereby contributing to its repression and initiating hermaphrodite sexual development. Similarly, might contribute to X-linked gene repression through recruitment of the dosage compensation complex to the X chromosomes in hermaphrodites. Seems to be involved in the depletion of histone H4 lysine 16 acetylation (H4K16ac) on dosage compensated X chromosomes. Plays a role in developmental rate and body fat regulation downstream of the TOR complex 2 pathway.
Subcellular Location
Nucleus. Chromosome.
Database Links

KEGG: cel:CELE_F52E10.1

STRING: 6239.F52E10.1

UniGene: Cel.17446

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