44805 Antibody

Code CSB-PA337002XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) Sep1 Polyclonal antibody
Uniprot No.
Target Names
Sep1
Alternative Names
Sep1 antibody; Diff6 antibody; iby antibody; CG1403 antibody; Septin-1 antibody; DIFF6 protein homolog antibody; Protein innocent bystander antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) 44805 protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Involved in cytokinesis (Probable). May be involved in p53-dependent apoptosis.
Gene References into Functions
  1. Phosphorylation of Pnut in the early stages of Drosophila embryo development affects association of the Sep1-Sep2 complex with the membrane and is important for viability. PMID: 29079679
  2. Sep1 is ubiquinated by Parkin and has a role in the neural cell death of autosomal recessive juvenile parkinsonism. PMID: 17456438
Subcellular Location
Cytoplasm.
Protein Families
TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily, Septin GTPase family
Tissue Specificity
Accumulates at the leading edge of the cleavage furrow in dividing cells and cellularizing embryos (at protein level). Also accumulates at the leading edge of the embryo epithelium during dorsal closure, in the embryonic neurons, and at the baso-lateral s
Database Links

KEGG: dme:Dmel_CG1403

STRING: 7227.FBpp0076897

UniGene: Dm.2682

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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