SEPTIN5 Antibody

Datasheet

Code	CSB-PA858724XA01HU
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) SEPTIN5 Polyclonal antibody

Uniprot No.

Q99719

Target Names

SEPTIN5

Alternative Names

5 Sep antibody; CDCrel 1 antibody; CDCREL antibody; CDCrel-1 antibody; CDCREL1 antibody; Cell division control related protein 1 antibody; Cell division control-related protein 1 antibody; H5 antibody; HCDCREL 1 antibody; OTTHUMP00000197271 antibody; OTTHUMP00000197272 antibody; OTTHUMP00000197273 antibody; OTTHUMP00000197274 antibody; OTTHUMP00000197275 antibody; OTTHUMP00000197276 antibody; OTTHUMP00000197396 antibody; OTTHUMP00000197410 antibody; Peanut like 1 antibody; Peanut like 1 homolog antibody; Peanut like protein 1 antibody; Peanut-like protein 1 antibody; Platelet glycoprotein Ib beta chain antibody; PNUTL1 antibody; SEPT5 antibody; SEPT5_HUMAN antibody; Septin 5 antibody; Septin-5 antibody

Raised in

Rabbit

Species Reactivity

Homo sapiens (Human)

Immunogen

Recombinant Homo sapiens (Human) SEPTIN5 protein

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Customer Reviews and Q&A

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Target Background

Function

Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). May play a role in platelet secretion.

Gene References into Functions

CDCrel-1 overexpression exerts dopamine-dependent neurotoxicity and may contribute to the development of autosomal-recessive juvenile parkinsonism PMID: 14530399
We studied the assembly of three human septins, SEPT4, SEPT5 and SEPT8, with each other (heterotypic) and with themselves (homotypic) using a yeast two-hybrid system. PMID: 15214843
the high expression levels of PNUTL1 in human pancreatic endocrine cells that suggests a similar role of this protein in islet cells to that demonstrated in neuronal tissues, and warrants further functional studies of this protein. PMID: 16179808
Our finding suggests a role for members of the septin family in the development of proliferative retinal membranes. PMID: 17625225
HSP70 and constitutively active HSF1 mediate protection against CDCrel-1-mediated toxicity PMID: 18398426

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Subcellular Location

Cytoplasm. Cytoplasm, cytoskeleton. Note=In platelets, found in areas surrounding alpha-granules.

Protein Families

TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily, Septin GTPase family

Tissue Specificity

Expressed at high levels in the CNS, as well as in heart and platelets (at protein level).

Database Links

HGNC: 9164

OMIM: 602724

KEGG: hsa:5413

STRING: 9606.ENSP00000391311

UniGene: Hs.728762

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Service

Phage Display Service

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Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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SEPTIN5 Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background