SERK1 Antibody

Code CSB-PA846408XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) SERK1 Polyclonal antibody
Uniprot No.
Target Names
SERK1
Alternative Names
SERK1 antibody; At1g71830 antibody; F14O23.21 antibody; F14O23_24 antibody; Somatic embryogenesis receptor kinase 1 antibody; AtSERK1 antibody; EC 2.7.10.1 antibody; EC 2.7.11.1 antibody; Somatic embryogenesis receptor-like kinase 1 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana SERK1 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Dual specificity kinase acting on both serine/threonine- and tyrosine-containing substrates. Phosphorylates BRI1 on 'Ser-887' and CDC48 on at least one threonine residue and on 'Ser-41'. Confers embryogenic competence. Acts redundantly with SERK2 as a control point for sporophytic development controlling male gametophyte production. Involved in the brassinolide signaling pathway. Probably required during small peptide (e.g. RGF1) signaling. Involved in the perception of phytosulfokine and subsequent signal transduction. Acts as a RLK5 coreceptor and promotes high-affinity IDA sensing, thus being a positive regulator of floral abscission.
Gene References into Functions
  1. Mutations in SERK1 restore floral organ shedding, Golgi structure and trans-Golgi network in nev mutant flowers. PMID: 20230490
  2. SERK1 is expressed in the procambial cells of the vascular bundle. PMID: 17630293
  3. The expression of AtSERK1::GUS coincides with embryogenic development up to the heart-shaped stage. Prior to the expression in embryos, AtSERK1 was expressed in single cells and small cell clusters, indicating that AtSERK1 marks embryogenic competence. PMID: 18515128
  4. essential for male microsporogenesis, independent from brassinolide PMID: 18667726
Subcellular Location
Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein Families
Protein kinase superfamily, Ser/Thr protein kinase family
Tissue Specificity
Expressed in flowers, tapetum, developing microspores, all cells of the embryo sac, provascular strands and developing vascular bundles. Low expression in adult vascular tissue. Detected in root meristem.
Database Links

KEGG: ath:AT1G71830

STRING: 3702.AT1G71830.1

UniGene: At.12027

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