SERK4 Antibody

Code CSB-PA890373XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) SERK4 Polyclonal antibody
Uniprot No.
Target Names
SERK4
Alternative Names
SERK4 antibody; BKK1 antibody; At2g13790 antibody; F13J11.14 antibody; Somatic embryogenesis receptor kinase 4 antibody; AtSERK4 antibody; EC 2.7.10.1 antibody; EC 2.7.11.1 antibody; Protein BAK1-like 1 antibody; AtBKK1 antibody; Somatic embryogenesis receptor-like kinase 2 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana SERK4 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Dual specificity kinase acting on both serine/threonine- and tyrosine-containing substrates. Positively regulates the BR-dependent plant growth pathway and negatively regulates the BR-independent cell-death pathway.
Gene References into Functions
  1. N-glycosylation and specific ERQC components are essential to activate bak1/serk4 cell death, and CRK4 is likely to be among client proteins of protein glycosylation involved in BAK1/SERK4-regulated cell death. PMID: 27250875
  2. Oligogalacturonides are sensed through multiple and partially redundant perception/transduction complexes, some targeted by AvrPto, but not necessarily comprising BAK1 and BKK1. PMID: 27118426
  3. SERK3 and SERK4 have diverged from the original SERK protein in both their extracellular and cytoplasmic domains. PMID: 25864910
  4. serk1 bak1 bkk1 triple mutant exhibited drastically reduced expression of a number of genes critical to polar auxin transport, cell cycle, endodermis development and root meristem differentiatio PMID: 22525267
  5. Data reveal that PAMP-triggered immunity (PTI) relies on ligand-induced recruitment of SERK3/4 and provides insight into the early PTI signaling events underlying this important layer of plant innate immunity. PMID: 21693696
  6. BAK7 (SERK4) is a component of the brassinosteroid signaling pathway, with varying degrees of genetic redundancy with BAK1. It affects plant growth via BL-independent pathways in vivo. PMID: 20108170
  7. study demonstrates that BAK1 and BKK1 (AtSERK4) have dual physiological roles: positively regulating a brassinosteroid (BR)-dependent plant growth pathway, and negatively regulating a BR-independent cell-death pathway PMID: 17600708

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Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Protein Families
Protein kinase superfamily, Ser/Thr protein kinase family
Database Links

KEGG: ath:AT2G13790

STRING: 3702.AT2G13790.1

UniGene: At.13851

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