set1 Antibody

1. we describe the impact of silencing and clustering on the mobility of an endogenous Tf2 element. Deletion of genes such as set1(+) or abp1(+) that both alleviate silencing and clustering, result in a corresponding increase in mobilization. Furthermore, expression of constitutively active Sre1, a transcriptional activator of Tf2 elements, also alleviates clustering and induces mobilization PMID: 27343236
2. Heterochromatin assembly and transcriptome repression is mediated by Set1 in coordination with Clr3. PMID: 25497836
3. the regulation of Set1 protein level is not coupled to the status of H3K4me or histone H2B ubiquitination by the HULC complex PMID: 25356590
4. The results suggest that meiotic DNA double-strand break formation is redundantly regulated by multiple chromatin-related factors including H3K9ac and Set1 in fission yeast. PMID: 23382177
5. An unexpected cooperation between Abp1 and the histone H3K4 methyltransferase Set1 was uncovered in regulating sense and antisense transcriptional silencing of Tf2 retrotransposons and Tf body integrity, largely independent of H3K4 methylation. PMID: 22907751
6. trans-histone crosstalk in S. pombe involves direct enhancement of Set1C methyltransferase activity by H2Bub1 and suggest that this represents a conserved aspect of H2Bub1-H3K4me crosstalk in eukaryotes. PMID: 22505722

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KEGG: spo:SPCC306.04c

STRING: 4896.SPCC306.04c.1