SET3 Antibody

Code CSB-PA339639XA01SVG
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) SET3 Polyclonal antibody
Uniprot No.
Target Names
SET3
Alternative Names
SET3 antibody; YKR029C antibody; SET domain-containing protein 3 antibody
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) SET3 protein
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Transcriptional regulator that acts via the formation of large multiprotein complexes that modify and/or remodel the chromatin. Required for both gene activation and repression. Part of the Set3C complex, which is required to repress early/middle sporulation genes during meiosis. Required for the transcriptional activation of genes with high activity.
Gene References into Functions
  1. Loss of HOS2 or components of the SET3 complex (SET3C) in which it acts specifically suppressed damage sensitivity and restored esa1 histone H4 acetylation. PMID: 26303527
  2. Unlike activators or repressors that act as an on/off switch of transcription, Set3C instead plays an important role in the timing of transcription response during gene activation or repression. PMID: 22959268
  3. analysis of distinct activities of the Rpd3(L) and Set3 histone deacetylase complexes PMID: 22683268
  4. Set3 may participate in the dynamic deposition and remodeling of Htz1-containing nucleosomes. PMID: 21288874
Protein Families
SET3 family
Database Links

KEGG: sce:YKR029C

STRING: 4932.YKR029C

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