set-9 Antibody

Code CSB-PA925066XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans set-9 Polyclonal antibody
Uniprot No.
Target Names
set-9
Alternative Names
set-9 antibody; F15E6.1 antibody; Histone-lysine N-methyltransferase set-9 antibody; EC 2.1.1.- antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans set-9 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Histone methyltransferase. Might play a role in transcriptional regulation. Together with set-26, negatively regulates lifespan in a germline-independent, partially daf-16-dependent fashion. Together with set-26, plays a role in germline development and maintenance and might play a role in the restriction of the trimethylation mark on histone H3 'Lys-4'(H3K4me3) to target genes specifically in the germline.
Gene References into Functions
  1. found that set-9 and set-26 partially act through the Forkhead box O (FOXO) transcription factor, DAF-16, to modulate lifespan PMID: 22212395
Subcellular Location
Nucleus.
Protein Families
Class V-like SAM-binding methyltransferase superfamily
Tissue Specificity
Predominantly expressed in the germline (at protein level).
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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