egg Antibody

Code CSB-PA654157XA01DLU
Size Enquire
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) egg Polyclonal antibody
Uniprot No.
Target Names
egg
Alternative Names
egg antibody; CG12196 antibody; Histone-lysine N-methyltransferase eggless antibody; EC 2.1.1.355 antibody; SETDB1 homolog antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) egg protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function
Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 in ovary. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting Su(var)205/HP1 to methylated histones. Plays a central role during oogenesis.
Gene References into Functions
  1. Study identified a H3K9 methyltransferase, SETDB1/eggless, a Drosophila homologue of the mammalian SETDB1, which confers the robustness for the precise determination of bristle number. PMID: 26914287
  2. Mosaic analysis also reveals that the early egg chamber budding defects in egg- ovaries are due to an intrinsic requirement for egg in follicle stem cells and their descendents PMID: 24485852
  3. The results showed that on chromosome 4, Su(var)3-9, SETDB1 and HP1a target the same genes. PMID: 23476027
  4. dSet1 is responsible for the bulk of H3K4 di- and trimethylation throughout Drosophila development. PMID: 22048023
  5. this study has revealed the essential roles of Eggless (Egg), a H3K9 methyltransferase in controlling stem cell maintenance and differentiation through distinct mechanisms. PMID: 22216012
  6. egg is required in the ovary for trimethylation of histone H3 at its K9 residue. PMID: 17164421
  7. results indicate that dSETDB1 and SU(VAR)3-9 act together with distinct roles during oogenesis, with dsetdb1 being of particular importance due to its germline stem cell-specific function and more severe mutant phenotype PMID: 18493619
  8. The genetic interactions between dSETDB1 and Su(var)3-9 mutations emphasize the importance of maintaining the activities of these histone methyltransferases in balance for normal genome function. PMID: 19189944
  9. Together with Egg, Wde localizes to euchromatin, is enriched on chromosome 4, and binds to the Painting of fourth (POF) protein. PMID: 19750210

Show More

Hide All

Subcellular Location
Nucleus. Chromosome.
Protein Families
Class V-like SAM-binding methyltransferase superfamily, Histone-lysine methyltransferase family, Suvar3-9 subfamily
Tissue Specificity
Expressed in ovary (at protein level).
Database Links
CUSABIO guaranteed quality
icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of address
Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2024 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1