mei-S332 Antibody

Code CSB-PA637583XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) mei-S332 Polyclonal antibody
Uniprot No.
Target Names
mei-S332
Alternative Names
mei-S332 antibody; CG5303 antibody; Shugoshin antibody; Meiotic protein S332 antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) mei-S332 protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Plays a central role in chromosome cohesion during meiosis and mitosis by preventing premature dissociation of cohesin complex from centromeres after prophase, when most of cohesin complex dissociates from chromosomes arms. May act by protecting or Rad21 from cleavage by Sse/separase. Required during meiosis in both males and females.
Gene References into Functions
  1. Wdb and Wrd contribute to MEI-S332's ability to ensure accurate segregation of sister chromatids but in centromere localization, they do not act solely downstream of MEI-S332. PMID: 29158400
Subcellular Location
Chromosome, centromere.
Protein Families
Shugoshin family
Database Links

KEGG: dme:Dmel_CG5303

STRING: 7227.FBpp0071675

UniGene: Dm.12274

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