SHE3 Antibody

Code CSB-PA327811XA01SVG
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) SHE3 Polyclonal antibody
Uniprot No.
Target Names
SHE3
Alternative Names
SHE3 antibody; YBR130C antibody; YBR1005 antibody; SWI5-dependent HO expression protein 3 antibody
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) SHE3 protein
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
RNA-binding protein that binds specific mRNAs including the ASH1 mRNA, coding for a repressor of the HO endonuclease. Part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud and in the daughter cell. Required for the delivery of cortical endoplasmic reticulum into the emerging bud.
Gene References into Functions
  1. Data indicate that the degradation of She3 by Grr1 is required for optimal cell growth. PMID: 23144720
  2. The cytoplasmic transport factor She3p displaces Loc1p from the ASH1 mRNP, allowing for the maturation of the localizing ASH1 mRNP. PMID: 24324176
  3. The adapter protein She3p tightly binds to the Myo4p rod, forming a single-headed motor complex. PMID: 22084309
  4. The present study reveals that the current accepted model for ASH1 mRNA localization does not fully account for the function of She3p in ASH1 mRNA localization. PMID: 19429778
Subcellular Location
Endoplasmic reticulum membrane; Peripheral membrane protein.
Protein Families
SHE3 family
Database Links

KEGG: sce:YBR130C

STRING: 4932.YBR130C

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