sig-7 Antibody

Datasheet

Code	CSB-PA962046XA01CXY
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Product Details
Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Caenorhabditis elegans sig-7 Polyclonal antibody

Uniprot No.

G5EEW6

Target Names

sig-7

Alternative Names

sig-7 antibody; F39H2.2 antibody; Peptidyl-prolyl cis-trans isomerase sig-7 antibody; EC 5.2.1.8 antibody; Cyclophilin-like protein sig-7 antibody; Silencer in germline 7 antibody

Raised in

Rabbit

Species Reactivity

Caenorhabditis elegans

Immunogen

Recombinant Caenorhabditis elegans sig-7 protein

Immunogen Species

Caenorhabditis elegans

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Customer Reviews and Q&A

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Target Background

Function

Probable PPIase that accelerates the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Involved in RNA polymerase II (RNA pol II)-mediated transcription elongation, and in primary transcript splicing, including co-transcriptional trans-splicing, in association with the catalytic subunit of the RNA pol II complex ama-1. Also plays a role in the regulation of elongation-dependent phosphorylation of ama-1 to control transcription. Involved in the transcription of several genes during embryogenesis and in particular, of genes related to developmental processes such as gastrulation, and also regulates transcription in germ cells from embryogenesis to adulthood.

Gene References into Functions

Our findings suggest that SIG-7 plays a central role in both Pol II elongation and co-transcriptional splicing and may provide an important link for their coordination and regulation PMID: 27541139

Subcellular Location

Nucleus, nucleoplasm. Chromosome.

Protein Families

Cyclophilin-type PPIase family, PPIL4 subfamily

Tissue Specificity

Ubiquitous.

Database Links

KEGG: cel:CELE_F39H2.2

STRING: 6239.F39H2.2a

UniGene: Cel.7694

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Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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