sin-3 Antibody

Code CSB-PA932420XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans sin-3 Polyclonal antibody
Uniprot No.
Target Names
sin-3
Alternative Names
sin-3 antibody; pqn-28 antibody; F02E9.4 antibody; Paired amphipathic helix protein sin-3 antibody; Histone deacetylase complex subunit sin-3 antibody; Transcriptional corepressor sin-3 antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans sin-3 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Probable transcriptional repressor required for the deposition of dimethylated 'Lys-9' of histone H3 (H3K9me2) on asynapsed chromosome pairs (both autosomes and sex chromosomes) during meiosis, but this does not seem to solely affect the transcriptional status. Plays a role in ray fusion and patterning in the male tail, and this may be through activity of the histone deacetylase complex (HDAC).
Gene References into Functions
  1. SIN-3 and its associated HDAC corepressor complex act as mediators of male sensory ray development PMID: 17506990
Subcellular Location
Nucleus.
Tissue Specificity
Expressed in all ray structural cells including ray 6, 7, 8 and 9 of the male tail. Also expressed in the inner labial neurons, socket cells, the cephalic neurons in the head and the ventral nerve cord.
Database Links

KEGG: cel:CELE_F02E9.4

STRING: 6239.F02E9.4b

UniGene: Cel.18986

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