SIW14 Antibody

Code CSB-PA344924XA01SVG
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) SIW14 Polyclonal antibody
Uniprot No.
Target Names
SIW14
Alternative Names
SIW14 antibody; OCA3 antibody; YNL032W antibody; N2746 antibody; Inositol phosphatase SIW14 antibody; EC 3.6.1.52 antibody; 5-PP-InsP phosphatase antibody; Inositol pyrophosphate phosphatase SIW14 antibody; Oxidant-induced cell-cycle arrest protein 3 antibody; Synthetic interaction with WHI2 protein 14 antibody
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) SIW14 protein
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Selectively cleaves the beta-phosphate at the 5-position of soluble inositol pyrophosphates. Converts 5-diphosphoinositol tetrakisphosphate (5-PP-InsP(4)) into inositol pentakisphosphate (InsP(5)), 5-diphosphoinositol pentakisphosphate (5-PP-IP(5) or 5-InsP(7)) into inositol hexakisphosphate (IP(6) or InsP(6)), and 1,5-bisdiphosphoinositol tetrakisphosphate (1,5-PP-IP(5) or InsP(8)) into 1-diphosphoinositol pentakisphosphate (1-PP-IP(5) or 1-InsP(7)). Modulates inositol pyrophosphate metabolism that may have an influence in stress response. Plays a role in actin filament organization and endocytosis. Functions as a prion suppressing factor possibly due to its phosphatase activity against inositol pyrophosphates, which are signal transduction molecules involved in prion propagation.
Gene References into Functions
  1. Siw14 is a novel inositol pyrophosphate phosphatase in Saccharomyces cerevisiae. PMID: 26828065
Subcellular Location
Cytoplasm.
Protein Families
Protein-tyrosine phosphatase family
Database Links

KEGG: sce:YNL032W

STRING: 4932.YNL032W

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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