SLD2 Antibody

Code CSB-PA786068XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) SLD2 Polyclonal antibody
Uniprot No.
Target Names
SLD2
Alternative Names
SLD2 antibody; At2g46210 antibody; T3F17.14 antibody; Delta(8)-fatty-acid desaturase 2 antibody; EC 1.14.19.29 antibody; Delta(8)-sphingolipid desaturase 2 antibody; Sphingoid long-chain base desaturase 2 antibody; Sphingoid LCB desaturase 2 antibody; Sphingolipid 8-(E/Z)-desaturase 2 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana SLD2 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Plays a major role as delta(8)-fatty-acid desaturase which introduces a double bond at the 8-position in the long-chain base (LCB) of ceramides with or without a hydroxy group at the 4-position. The enzyme produces both the 8E and 8Z isomers (in a 4:1 ratio). This structural modification contributes to the quantitative partitioning of ceramides between the two major sphingolipid classes, glucosylceramides and glycosylinositolphosphoryl ceramides. Sphingolipids are important membrane components involved in environmental stress responses, such as resistance to chilling, and act as cell signaling molecules.
Gene References into Functions
  1. AtSLD1 and AtSLD2 are responsible for all of the sphingolipid Delta8 unsaturation in Arabidopsis, and AtSLD1 is the predominant contributor to unsaturation in all of the organs examined. PMID: 22023480
Subcellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein Families
Fatty acid desaturase type 1 family
Tissue Specificity
Highly expressed in flowers and siliques. Expressed at low levels in roots, leaves and stems.
Database Links

KEGG: ath:AT2G46210

STRING: 3702.AT2G46210.1

UniGene: At.36539

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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