SLX8 Antibody

Code CSB-PA310437XA01SXV
Product Type Polyclonal Antibody
Uniprot No. P87176
Delivery Make-to-order
Protocols ELISA Protocol
Immunogen Recombinant Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) SLX8 protein
Raised in Rabbit
Species Reactivity Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Tested Applications ELISA, WB (ensure identification of antigen)
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method Protein A/G
Isotype IgG
Clonality Polyclonal
Alias E3 ubiquitin-protein ligase complex slx8-rfp subunit slx8 (EC (RING finger protein slx8) (RING-dependent E3 ubiquitin-protein ligase slx8) (RING-type E3 ubiquitin transferase slx8) (Synthetic lethal of unknown function protein 8) slx8 SPBC3D6.11c
Immunogen Species Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Gene Names slx8
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Mediates ubiquitination and subsequent desumoylation/degradation of sumoylated proteins and proteins containing SUMO-like domains. Acts as a critical suppressor of gross chromosomal rearrangements (GCRs) during normal cell cycle progression. Involved in stabilizing, restarting or resolving transiently stalled replication forks. Prevents accumulation of DNA damage during cell cycle progression (By similarity).
Subcellular Location Nucleus
Database Links

KEGG: spo:SPBC3D6.11c

STRING: 4896.SPBC3D6.11c.1

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