slyD Antibody

Code CSB-PA364349XA01SZB
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Product Details

Full Product Name
Rabbit anti-Shigella flexneri slyD Polyclonal antibody
Uniprot No.
Target Names
slyD
Alternative Names
slyD antibody; SF3367 antibody; S4395 antibody; FKBP-type peptidyl-prolyl cis-trans isomerase SlyD antibody; PPIase antibody; EC 5.2.1.8 antibody; Metallochaperone SlyD antibody
Raised in
Rabbit
Species Reactivity
Shigella flexneri
Immunogen
Recombinant Shigella flexneri slyD protein
Immunogen Species
Shigella flexneri
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Folding helper with both chaperone and peptidyl-prolyl cis-trans isomerase (PPIase) activities. Chaperone activity prevents aggregation of unfolded or partially folded proteins and promotes their correct folding. PPIases catalyze the cis-trans isomerization of Xaa-Pro bonds of peptides, which accelerates slow steps of protein folding and thus shortens the lifetime of intermediates. Both strategies lower the concentration of intermediates and increase the productivity and yield of the folding reaction. SlyD could be involved in Tat-dependent translocation, by binding to the Tat-type signal of folded proteins.; Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step. This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity.
Subcellular Location
Cytoplasm.
Protein Families
FKBP-type PPIase family
Database Links

KEGG: sfl:SF3367

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