sma-5 Antibody

Code CSB-PA909865XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans sma-5 Polyclonal antibody
Uniprot No.
Target Names
sma-5
Alternative Names
sma-5 antibody; W06B3.2 antibody; Mitogen-activated protein kinase sma-5 antibody; EC 2.7.11.24 antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans sma-5 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Serine/threonine-protein kinase involved in the postembryonic regulation of body size, mainly through control of cell growth. In particular, controls the volume of intestine, muscles and hypodermis. In addition, regulates growth, intestinal granule distribution, lifespan and number of offspring.
Gene References into Functions
  1. Sequencing the entire sma-5 gene of kc1 animals showed that the gene contains a single point mutation (position 998 in CELE_W06B3.2a) resulting in a change of R125 (CGC) into H125 (CAC) PMID: 27733627
  2. sma-5 functions in a MAP kinase pathway to regulate body size mainly through control of cell growth PMID: 15944183
Protein Families
Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily
Tissue Specificity
Expressed in intestine with a stronger expression in the four most anterior cells, muscles, excretory cell, pharynx and, to a lesser extent, in hypodermis.
Database Links

KEGG: cel:CELE_W06B3.2

STRING: 6239.W06B3.2c

UniGene: Cel.19791

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