Marcal1 Antibody

Code CSB-PA896122XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) Marcal1 Polyclonal antibody
Uniprot No.
Target Names
Marcal1
Alternative Names
Marcal1 antibody; CG3753 antibody; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 antibody; EC 3.6.4.- antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) Marcal1 protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
ATP-dependent annealing helicase that catalyzes the rewinding of the stably unwound DNA.
Gene References into Functions
  1. limination of the ATP-binding activity of Marcal1 also reduced annealing-dependent repair, suggesting that the annealing activity requires translocation along DNA. Unlike the null mutant, however, the ATP-binding defect mutant showed reduced end joining, shedding light on the interaction between SDSA and end-joining pathways. PMID: 28258182
  2. deficiency of a SMARCAL1 ortholog altering the chromatin structure of a gene PMID: 27813696
Subcellular Location
Nucleus.
Protein Families
SNF2/RAD54 helicase family, SMARCAL1 subfamily
Database Links

KEGG: dme:Dmel_CG3753

STRING: 7227.FBpp0078631

UniGene: Dm.18320

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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