smg Antibody

Datasheet

Code	CSB-PA630497XA01DLU
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Product Details

Full Product Name

Rabbit anti-Drosophila melanogaster (Fruit fly) smg Polyclonal antibody

Uniprot No.

Q23972

Target Names

smg

Alternative Names

smg antibody; CG5263 antibody; Protein Smaug antibody

Raised in

Rabbit

Species Reactivity

Drosophila melanogaster (Fruit fly)

Immunogen

Recombinant Drosophila melanogaster (Fruit fly) smg protein

Immunogen Species

Drosophila melanogaster (Fruit fly)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Translation regulator that binds to the 3'-UTR of specific mRNAs such as nanos (nos) and prevents their translation. Prevents translation of unlocalized nos in the bulk cytoplasm via the recruitment of cup.

Gene References into Functions

Smaug regulates the expression of mRNAs encoding glycolytic enzymes (hexokinase and phosophofructokinase), a proteasome regulatory subunit (Rpn7) as well as epigenetic (Su(z)12) and post-transcriptional (Bicaudal C) regulators. PMID: 24393533
This paper reports that the Smaug recognition elements in the 3' UTR of nanos (nos) mRNA govern the time- and ATP-dependent assembly of an exceedingly stable repressed ribonucleoprotein particle (RNP) in embryo extract. PMID: 21081899
smaug has a domain that encodes a RNA-binding motif PMID: 12372396
RNA binds via the SAM domain of smaug. PMID: 12820967
the sterile-alpha motif (SAM) domain of Smaug functions as an RNA-recognition domain PMID: 12858164
Smaug recruits the CCR4/POP2/NOT deadenylase complex to trigger maternal transcript localization in the early Drosophila embryo. PMID: 15723788
Smaug accumulation thus coordinates progression through the maternal-to-zygotic transition PMID: 19234062

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Subcellular Location

Cytoplasm. Note=In the cytoplasm of syncytial embryos, accumulates in discrete foci.

Protein Families

SMAUG family

Tissue Specificity

At syncytial blastoderm, it is located throughout the bulk cytoplasm and pole plasm. By the time of cellularization, it concentrates at the posterior pole.

Database Links

KEGG: dme:Dmel_CG5263

STRING: 7227.FBpp0288542

UniGene: Dm.2553

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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smg Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background