smg-8 Antibody

Datasheet

Code	CSB-PA524002XA01CXY
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Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Caenorhabditis elegans smg-8 Polyclonal antibody

Uniprot No.

O62301

Target Names

smg-8

Alternative Names

smg-8 antibody; K04B12.3 antibody; Protein smg-8 antibody; Suppressor with morphogenetic effect on genitalia protein 8 antibody

Raised in

Rabbit

Species Reactivity

Caenorhabditis elegans

Immunogen

Recombinant Caenorhabditis elegans smg-8 protein

Immunogen Species

Caenorhabditis elegans

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Probable component of kinase complex containing smg-1 and recruited to stalled ribosomes.

Gene References into Functions

Results found that SMG8-SMG9 is a G-domain heterodimer with architectural similarities to the dynamin-like family of GTPases. The SMG8-SMG9 heterodimer forms in the absence of nucleotides. Nucleotide binding occurs at the G domain of SMG9 but not of SMG8. PMID: 28389433
Genetic characterization of smg-8 mutants reveals no role in C. elegans nonsense mediated decay. PMID: 23166684

Protein Families

SMG8 family

Database Links

KEGG: cel:CELE_K04B12.3

STRING: 6239.K04B12.3

UniGene: Cel.34193

Promotions

Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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smg-8 Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background