Smarcc1 Antibody

1. Conditional deletion of BAF155 causes impaired proliferation of olfactory neurons and defective axonogenesis in the developing olfactory epithelium. PMID: 27611684
2. BAF155 mediates the interaction between BAF complexes and H3K27demethylases, controlling the global level of H3K27me2/3 and ultimately the gene expression program in cortical development. PMID: 26655900
3. the role of BAF155 in late pre-implantation stages of mouse embryos PMID: 26952987
4. the increased frequency of Treg cells in the spinal cord of beta-actin-SRG3 Tg mice might induce the suppression of and accelerate the recovery from EAE symptoms. PMID: 26147219
5. Deletion of either Brg1 in the subependymal zone (SEZ) causes the progeny of adult neural stem cells to convert to the ependymal lineage within the SEZ while migrating neuroblasts convert to different glial lineages en route to or in the olfactory bulb. PMID: 23933087
6. Characterization of a missense mutation allele of the Smarcc1 gene (Smarcc1msp3 or Baf155msp3); lends new insight into the functions of the BAF chromatin remodeling complex during the critical stage of neural tube closure PMID: 24170322
7. we identify BAF155 as a substrate for arginine methyltransferase CARM1. PMID: 24434208
8. Wwp2 acts as a ubiquitin ligase of SRG3. PMID: 24365151
9. CHFR interacts with BRG1, SNF5, and BAF60a of the SWI/SNF-like BAF complex and ubiquitinates them to target for degradation through a proteasome-mediated pathway; SRG3 stabilizes these components by blocking their interaction with CHFR. PMID: 22285184
10. Our results establish a novel function of Srg3 in tumor suppression PMID: 20935679
11. report that members of the PBAF chromatin remodeling complex, including Smarca4/Brg1, Smarcb1/Baf47, Smarcc1/Baf155, and Smarce1/Baf57, are required for the repression of Nanog and other self-renewal gene expression upon mouse ESC (mESC) differentiation. PMID: 19785031
12. the SWI/SNF complex plays a critical role during T cell activation and subsequent immune responses PMID: 19910461
13. TCR signals result in GC desensitization in immature T cells by repressing SRG3 gene expression via Ras activation PMID: 15016814
14. SRG3 down-regulation has a role in E2A/HEB and Id3 proteins control of sensitivity to glucocorticoid-induced apoptosis in thymocytes PMID: 15016815
15. SRG3 expression in thymus is repressed by nitric oxide in an anti-apoptotic process PMID: 15187086
16. Results suggest that the multiple positive regulatory mechanisms of androgen receptor transactivation by SWI3-related gene product (SRG3) may be important for the rapid proliferation of prostate cells during prostate development and regeneration. PMID: 15923603
17. results suggest that diverse interactions between Sp1/Sp3 and Ets factors are crucial for the SRG3 gene expression PMID: 16288722
18. SRG3 is essential for extra-embryonic vascular development. PMID: 18206867

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KEGG: mmu:20588

STRING: 10090.ENSMUSP00000086094

UniGene: Mm.85410