SNA3 Antibody

Code CSB-PA318513XA01SVG
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) SNA3 Polyclonal antibody
Uniprot No.
Target Names
SNA3
Alternative Names
SNA3; YJL151C; J0630; Protein SNA3
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) SNA3 protein
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Gene References into Functions
  1. Sna3 is a potential competitor of Bul1 for the Rsp5 WW domain affecting degradation of tryptophan permease Tat2. PMID: 19944104
  2. These results uncover a series of determinants impacting Sna3 multivesicular bodies sorting, including unexpected roles for Rsp5. PMID: 17182849
  3. Sna3 circumvents Ub-mediated recognition by interacting directly with Rsp5, an E3 Ub ligase that catalyzes monoubiquitination of multivesicular bodies vesicle cargoes. PMID: 17182850
  4. Sna3p sorting depends on a direct interaction between a PPAY motif within its C-terminal cytosolic tail and the WW domains of Rsp5p. PMID: 17332499
  5. Sna3p undergoes Rsp5-dependent polyubiquitylation with K63-linked ubiquitin chains during its sorting to the endosomal pathway. PMID: 17645729

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Subcellular Location
Membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein. Vacuole lumen. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=Sorted via late endosomes to the vacuolar lumen in a ubiquitin-independent manner.
Protein Families
UPF0057 (PMP3) family
Database Links

KEGG: sce:YJL151C

STRING: 4932.YJL151C

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