SNF8 Antibody

Datasheet
Code CSB-PA529719XA01SXV
Product Type Polyclonal Antibody
Uniprot No. O94663
Delivery Make-to-order
Protocols ELISA Protocol
Immunogen Recombinant Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) SNF8 protein
Raised in Rabbit
Species Reactivity Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Tested Applications ELISA, WB (ensure identification of antigen)
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method Protein A/G
Isotype IgG
Clonality Polyclonal
Alias Vacuolar-sorting protein dot2 (Defective organization of telomere protein 2) (ELL-associated protein of 30 kDa homolog dot2) dot2 SPBC651.05c
Immunogen Species Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Gene Names dot2
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. Negatively regulates meiotic spindle pole body maturation via indirect regulation of the pcp1 gene. Required for efficient entry into pre-meiotic S phase.
Subcellular Location Cytoplasm, Nucleus, Endosome membrane, Peripheral membrane protein
Protein Families SNF8 family
Database Links

KEGG: spo:SPBC651.05c

STRING: 4896.SPBC651.05c.1

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