Snmp1 Antibody

Code CSB-PA892713XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) Snmp1 Polyclonal antibody
Uniprot No.
Target Names
Snmp1
Alternative Names
Snmp1 antibody; CG7000Sensory neuron membrane protein 1 antibody; SNMP1Dmel antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) Snmp1 protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Plays an olfactory role that is not restricted to pheromone sensitivity. Has a role in detection and signal transduction of the fatty-acid-derived male pheromone 11-cis vaccenyl acetate (cVA). Not required for sensitivity to general odorants. Acts in concert with Or67d and lush to capture cVA molecules on the surface of Or67d expressing olfactory dendrites and facilitate their transfer to the odorant-receptor Orco complex. Essential for the electrophysiological responses of these olfactory sensory neurons (OSNs) to cVA. Not required for the development of trichoid OSNs and support cells.
Gene References into Functions
  1. SNMP1 funnels hydrophobic pheromones from the extracellular fluid to integral membrane receptors. PMID: 27302750
  2. Our results thus clarify SNMP1 as an important player required for the rapid kinetics of the pheromone response in insects. PMID: 25255106
  3. a Drosophila melanogaster CD36 homologue, Sensory neuron membrane protein (SNMP), is expressed in a population of olfactory sensory neurons (OSNs) implicated in pheromone detection. PMID: 17943085
  4. SNMP is a signaling component required for pheromone sensitivity in Drosophila. PMID: 18653762
Subcellular Location
Cell membrane; Multi-pass membrane protein.
Protein Families
CD36 family
Tissue Specificity
Selectively expressed in antenna. Expressed in lateral-distal population of OSNs that coexpress Orco, in non-neuronal support cells that surround these OSNs, in support cells elsewhere in the antenna and chemosensory organs on the proboscis. Expressed in
Database Links

KEGG: dme:Dmel_CG7000

STRING: 7227.FBpp0306056

UniGene: Dm.27587

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