sod-1 Antibody

Datasheet

Code	CSB-PA022397XA01CXY
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Product Details

Full Product Name

Rabbit anti-Caenorhabditis elegans sod-1 Polyclonal antibody

Uniprot No.

P34697

Target Names

sod-1

Alternative Names

sod-1 antibody; C15F1.7 antibody; Superoxide dismutase [Cu-Zn] antibody; EC 1.15.1.1 antibody

Raised in

Rabbit

Species Reactivity

Caenorhabditis elegans

Immunogen

Recombinant Caenorhabditis elegans sod-1 protein

Immunogen Species

Caenorhabditis elegans

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

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Target Background

Function

Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Required for normal brood size. May be involved in regulating mpk-1 phosphorylation downstream of phosphatase ptp-2 during oocyte maturation.

Gene References into Functions

We found that guanylyl cyclases GCY-5 and GCY-22 and neuropeptide receptor NPR-1 act antagonistically to regulate SOD-1 expression in the gustatory neuron ASER. PMID: 29857312
These data suggest that SOD1 mutants are removed from the nucleus by CRM1 as a defense mechanism against proteotoxicity of misfolded SOD1 in the nucleus. PMID: 28463106
a post-translational modification to the inactive enzyme during hypoxia PMID: 22148750
SOD isoforms play no role in lifespan in ad lib or dietary restricted conditions, but mutational inactivation of SOD-1 reduces life extension by cold. PMID: 19059428
the ALS-linked mutant SOD1 produces a locomotor defect associated with aggregation and synaptic dysfunction when expressed in neurons of Caenorhabditis elegans PMID: 19165329
this suggests that the activity of SOD-1, which so far has been thought to act mainly in cytoplasm, helps to control the detoxification of *O2- also in the mitochondria. PMID: 19282511

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Subcellular Location

Cytoplasm.

Protein Families

Cu-Zn superoxide dismutase family

Database Links

KEGG: cel:CELE_C15F1.7

STRING: 6239.C15F1.7a

UniGene: Cel.19756

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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sod-1 Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background