sop-2 Antibody

Datasheet

Code	CSB-PA822152XA01CXY
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Product Details

Full Product Name

Rabbit anti-Caenorhabditis elegans sop-2 Polyclonal antibody

Uniprot No.

Q965H3

Target Names

sop-2

Alternative Names

sop-2 antibody; C50E10.4 antibody; Polycomb protein sop-2 antibody; Suppressor of pal-1 protein 2 antibody

Raised in

Rabbit

Species Reactivity

Caenorhabditis elegans

Immunogen

Recombinant Caenorhabditis elegans sop-2 protein

Immunogen Species

Caenorhabditis elegans

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

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Target Background

Function

Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. Also required to repress expression of other genes and for localization of sor-1. Binds RNA.

Gene References into Functions

Polycomb-like genes in Caenorhabditis elegans, sop-2 and sor-3, regulate the formation of dopaminergic and serotonergic neurons and several other neuronal properties PMID: 17215367
SOP-2 binds to RNA via 3 RNA binding domains. PMID: 15200961
SOR-1 and SOP-2 directly interact with each other and are colocalized in nuclear bodies PMID: 16501168
These studies reveal that sop-2 integrates spatial, temporal, and sexual cues during C. elegans development. PMID: 18245856
microRNAs may contribute to the tight restriction of egl-5 expression to particular cell lineages PMID: 19235721

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Subcellular Location

Nucleus. Note=Forms subnuclear bodies.

Tissue Specificity

Widely expressed. Weakly expressed in most somatic cells of 50-cell stage embryos. At 200 cell stage, it is strongly expressed. By comma stage, it is expressed in most somatic cells.

Database Links

STRING: 6239.C50E10.4

UniGene: Cel.15633

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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sop-2 Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background