sopD Antibody

Code CSB-PA336770XA01SXB
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Product Details

Full Product Name
Rabbit anti-Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) sopD Polyclonal antibody
Uniprot No.
Target Names
sopD
Alternative Names
sopD antibody; STM2945 antibody; Secreted effector protein SopD antibody; Salmonella outer protein D antibody
Raised in
Rabbit
Species Reactivity
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Immunogen
Recombinant Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) sopD protein
Immunogen Species
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. Contributes to replication in macrophages. Plays a role, cooperatively with SopB, in membrane fission and macropinosome formation during invasion.
Gene References into Functions
  1. Findings demonstrate that type III secretion of SopD involves multiple signals and protein interactions, providing important mechanistic insights into effector protein secretion. PMID: 20185511
  2. results indicate that both SopD and SopD2 contribute to virulence in mice and suggest a functional relationship between these two proteins during systemic infection of the host. PMID: 15554961
Subcellular Location
Secreted. Host cytoplasm. Host cell membrane.
Protein Families
SopD family
Database Links

KEGG: stm:STM2945

STRING: 99287.STM2945

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