ost-1 Antibody

Code CSB-PA022486XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans ost-1 Polyclonal antibody
Uniprot No.
Target Names
ost-1
Alternative Names
ost-1 antibody; sparc antibody; C44B12.2 antibody; SPARC antibody; Basement-membrane protein 40 antibody; BM-40 antibody; Osteonectin antibody; ON antibody; Secreted protein acidic and rich in cysteine antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans ost-1 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Has a high affinity for collagen. Affects nematode body morphology and mobility. Essential for C.elegans development and muscle function. The cysteine-rich region could have protease inhibitory activity or may provide the framework for a protein binding module. Probable role in skeletal morphogenesis.
Gene References into Functions
  1. SPARC functions normally to traffic collagen from its site of synthesis to tissues that do not express collagen.SPARC promotes anchor cell invasion by decreasing type IV collagen levels in the basement membrane. PMID: 26926673
Subcellular Location
Secreted, extracellular space, extracellular matrix, basement membrane.
Protein Families
SPARC family
Tissue Specificity
Expressed by body wall and sex muscle cells. Probable association with basement membranes.
Database Links

KEGG: cel:CELE_C44B12.2

STRING: 6239.C44B12.2

UniGene: Cel.17507

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