spvB Antibody

Code CSB-PA324196XA01SWX
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Product Details

Full Product Name
Rabbit anti-Salmonella typhimurium spvB Polyclonal antibody
Uniprot No.
Target Names
spvB
Alternative Names
spvB antibody; mkaA antibody; Mono(ADP-ribosyl)transferase SpvB antibody; mADPRT antibody; mART antibody; EC 2.4.2.31 antibody; 65 kDa virulence protein antibody; NAD(+)--arginine ADP-ribosyltransferase antibody; Toxin SpvB antibody
Raised in
Rabbit
Species Reactivity
Salmonella typhimurium
Immunogen
Recombinant Salmonella typhimurium spvB protein
Immunogen Species
Salmonella typhimurium
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Mono-ADP-ribosylates eukaryotic muscle and non-muscle actin on 'Arg-177'. ADP-ribosylates all actins tested, has more activity on nonmuscle beta/gamma-actin than on muscle alpha-actin. Prefers monomeric G-actin but can weakly ADP-ribosylate F-actin. ADP-ribosylation prevents the polymerization of G-actin to F-actin, causing actin filament depolymerization, destruction of the cytoskeleton and cytotoxicity. Does not possess NAD(+)-glycohydrolase activity, unlike most mART enzymes.
Subcellular Location
Secreted.
Protein Families
SpvB family
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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