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  • Peptide

spx Antibody

Datasheet
Code CSB-PA557730XA01DIL
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Product Details

Full Product Name
Rabbit anti-Danio rerio (Zebrafish) (Brachydanio rerio) spx Polyclonal antibody
Uniprot No.
F1QQI2
Target Names
spx
Alternative Names
spx antibody; si:dkey-13i19.7 antibody; Spexin prohormone 1 antibody; Neuropeptide Q antibody; Spexin hormone) [Cleaved into: Spexin-1 antibody; Spexin-14)] antibody
Raised in
Rabbit
Species Reactivity
Danio rerio (Zebrafish) (Brachydanio rerio)
Immunogen
Recombinant Danio rerio (Zebrafish) (Brachydanio rerio) spx protein
Immunogen Species
Danio rerio (Zebrafish) (Brachydanio rerio)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
ELISA Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Plays a role in the regulation of food intake and energy metabolism. May also be involved in suppressing the anxiety response by promoting the expression of serotonin-related genes such as fev, tph2 and slc6a4a.; Acts as a ligand for galanin receptors galr2a and galr2b. Brain administration of the peptide inhibits food consumption and elevates levels of glucose, triacylglycerol and cholesterol in the serum. Likely to control food intake by regulating appetite related genes which includes the negative regulation of the orexigenic factor agrp. By controlling food intake it may act as a satiety factor in energy metabolism.
Subcellular Location
[Spexin-1]: Secreted. Secreted, extracellular space. Cytoplasmic vesicle, secretory vesicle.
Tissue Specificity
Mainly expressed in the brain and ovary. Detected bilaterally in the adult brainstem. Expressed in neurons in the dorsal habenula (dHb). In the dHb some neurons project into the interpeduncular nucleus (IPN) where expression often overlaps with galr2a and
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