Src64B Antibody

1. Src64 controls actin dynamics to mediate proper ring canal formation during incomplete cytokinesis during germline cyst development in vivo PMID: 26628094
2. a novel essential role for Src in intestinal stem/progenitor cell proliferation and tumourigenesis initiation in vivo. PMID: 24788409
3. Mutations in a Drosophila src gene, src64, that alter the three HRD amino acids, were identified. PMID: 22132220
4. Maternal src64 regulates microfilament contraction throughout cellularization, but that zygotic src64 makes a small, but normally nonessential, contribution during late cellularization. PMID: 21735539
5. Src64B overexpression induced the formation of specialized haemocytes (lamellocytes), but had no effect on circulating plasmatocyte concentration. Src64B overexpression induced F-actin formation and Jun kinase activation in plasmatocytes. PMID: 20375590
6. Src64 acts in a cell-autonomous fashion and is likely to interact with the previously-identified linotte/derailed receptor tyrosine kinase in mushroom body development PMID: 14608664
7. Src64 is involved in fusome development and karyosome formation during Drosophila oogenesis. PMID: 15979065
8. Study shows that in Drosophila epithelia in situ, levels of Src signaling determine the cellular outcome of Src activation; apoptotic cell death was triggered at high Src levels; lower levels directed antiapoptotic signals while promoting proliferation. PMID: 17974969
9. Src64B is required for tracheal development and to increase the rate of adherens junction turnover. PMID: 18305002

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KEGG: dme:Dmel_CG7524

STRING: 7227.FBpp0293527

UniGene: Dm.1531