B52 Antibody

Datasheet

Code	CSB-PA328642XA01DLU
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Product Details

Full Product Name

Rabbit anti-Drosophila melanogaster (Fruit fly) B52 Polyclonal antibody

Uniprot No.

P26686

Target Names

B52

Alternative Names

B52 antibody; E(Dfd) antibody; RS55 antibody; SR55 antibody; CG10851 antibody; Serine-arginine protein 55 antibody; SRP55 antibody; 52 kDa bracketing protein antibody; B52 protein antibody; Protein enhancer of deformed antibody

Raised in

Rabbit

Species Reactivity

Drosophila melanogaster (Fruit fly)

Immunogen

Recombinant Drosophila melanogaster (Fruit fly) B52 protein

Immunogen Species

Drosophila melanogaster (Fruit fly)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Essential for development. May have a critical role in splicing or in controlling alternative splice site use of at least some pre-mRNA in vivo. Not required for all splicing. May play a general role in the condensation or decondensation of chromatin.

Gene References into Functions

Loss of B52 increases growth of axon branches. B52 function is also required for Choline acetyltransferase (ChAT ) splicing. PMID: 27725692
B52 overexpression increases cell growth, upregulates myc transcription, and gives rise to flies lacking thoracic bristles. PMID: 25680814
B52/SRp55 generates 2 isoforms of eyeless differing by an alternative exon encoding a 60-AA insert at the beginning of the paired domain. In normal eye development B52/SRp55 controls eye organogenesis & size by regulating eyeless alternative splicing. PMID: 17327915
The SR proteins dASF/SF2 and B52 caused defects in ommatidia structure, and B52 impaired normal axonal projections of photoreceptors and neurogenesis in visual ganglia. PMID: 17283056

Subcellular Location

Nucleus. Note=Associated with boundaries of transcriptionally active chromatin.

Protein Families

Splicing factor SR family

Database Links

KEGG: dme:Dmel_CG10851

UniGene: Dm.2188

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Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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B52 Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background