SRX Antibody

Code CSB-PA965472XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) SRX Polyclonal antibody
Uniprot No.
Target Names
SRX
Alternative Names
SRX antibody; At1g31170 antibody; F28K20.12Sulfiredoxin antibody; chloroplastic/mitochondrial antibody; AtSRX antibody; EC 1.8.98.2 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana SRX protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in a peroxiredoxin. May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase. Required to switch on the antioxidant pathway to regenerate the oxidative damage. In mitochondrion, catalyzes the retroreduction of the inactive sulfinic form of atypical Prx IIF using thioredoxin as reducing agent.
Gene References into Functions
  1. Srx functions as a nuclease enzyme that can use single-stranded and double-stranded DNAs as substrates. PMID: 22967894
  2. Srx is present in mitochondria regardless of the redox state. It retroreduces the inactive sulfinic form of atypical Prx IIF. PMID: 21139087
  3. AtSrx is a chloroplastic enzyme displaying sulfinic acid reductase activity. PMID: 17217469
Subcellular Location
Plastid, chloroplast. Mitochondrion.
Protein Families
Sulfiredoxin family
Tissue Specificity
Low expression in photosynthetic tissues such as leaves and sepals.
Database Links

KEGG: ath:AT1G31170

STRING: 3702.AT1G31170.4

UniGene: At.40405

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