SSD1 Antibody

Code CSB-PA326463XA01SVG
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) SSD1 Polyclonal antibody
Uniprot No.
Target Names
SSD1
Alternative Names
SSD1 antibody; CLA1 antibody; RLD1 antibody; SRK1 antibody; YDR293C antibody; D9819.4 antibody; Protein SSD1 antibody; Protein SRK1 antibody
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) SSD1 protein
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Can suppress the lethality due to deletion of SIT4, and partially the defects due to BCY1 disruption. Is implicated in the control of the cell cycle G1 phase.
Gene References into Functions
  1. Ssd1 regulates translation of its target message primarily through UTRs and the SIM1 message through multiple potential points of interaction, permitting fine translational control in various contexts. PMID: 24465507
  2. Both SSD1 and PDE2 seemed to improve ethanol tolerance by maintaining robustness of the yeast cell wall. PMID: 22380741
  3. There is an Ssd1p-dependent cross-talk between chromosomal positioning within the nucleus and the positioning of cellular components within the cell in Saccharomyces cerevisiae. PMID: 21897045
  4. Ssd1p expressed from SSD1-V, but not from ssd1-d, stabilizes a subpopulation of CLN2 mRNA in wild-type and taf1-N568Delta strains and facilitates the continuous transcription of CLN2 after heat shock in the taf1-N568Delta strain. PMID: 20977549
  5. The V allele of SSD1 defines a previously undescribed pathway affecting cellular longevity and is necessary for cells to achieve extremely long life span. PMID: 15126388
  6. RAM proteins and Ssd1p function cooperatively to control cell integrity while Zrg8p and Srl1p function as nonessential inhibitors of Ssd1p. PMID: 15972461
  7. Results compare mRNA levels in an isogenic pair of mutant (ssd1-d) and wild-type (SSD1-V) cells across the cell cycle, and show that SSD1-V also dramatically increases chronological life span . PMID: 19570907

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Protein Families
RNR ribonuclease family
Database Links

KEGG: sce:YDR293C

STRING: 4932.YDR293C

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