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SSL1 Antibody
Code CSB-PA312019XA01SVG Size Enquire Have Questions? Leave a Message or Start an on-line Chat Product Details
Full Product NameRabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) SSL1 Polyclonal antibodyUniprot No.Target NamesSSL1Alternative NamesSSL1 antibody; YLR005W antibody; General transcription and DNA repair factor IIH subunit SSL1 antibody; TFIIH subunit SSL1 antibody; RNA polymerase II transcription factor B subunit SSL1 antibody; TFB subunit SSL1 antibody; Suppressor of stem-loop protein 1 antibodyRaised inRabbitSpecies ReactivitySaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)ImmunogenRecombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) SSL1 proteinImmunogen SpeciesSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)ConjugateNon-conjugatedClonalityPolyclonalIsotypeIgGPurification MethodAntigen Affinity PurifiedConcentrationIt differs from different batches. Please contact us to confirm it.BufferPreservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4FormLiquidTested ApplicationsELISA, WB (ensure identification of antigen)ProtocolsTroubleshooting and FAQsStorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.Value-added Deliverables① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);Quality Guarantee① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;Lead TimeMade-to-order (14-16 weeks)UsageFor Research Use Only. Not for use in diagnostic or therapeutic procedures.Related Products
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Target Background
FunctionComponent of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.Gene References into Functions- The binding of Ssl1/p44 contributes to the helicase activity of Rad3/XPD and cell viability. PMID: 25681444
Subcellular LocationNucleus.Protein FamiliesGTF2H2 familyDatabase LinksKEGG: sce:YLR005W
STRING: 4932.YLR005W
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