Product Details

Full Product Name

Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) SSRP1 Polyclonal antibody

Uniprot No.

Q05153

Target Names

SSRP1

Alternative Names

SSRP1 antibody; HMGB8 antibody; NFD8 antibody; At3g28730 antibody; T19N8.2 antibody; FACT complex subunit SSRP1 antibody; Facilitates chromatin transcription complex subunit SSRP1 antibody; High mobility group B protein 8 antibody; Nucleosome/chromatin assembly factor group D 08 antibody; Nucleosome/chromatin assembly factor group D 8 antibody; Protein NUCLEAR FUSION DEFECTIVE 8 antibody; Recombination signal sequence recognition protein 1 antibody

Raised in

Rabbit

Species Reactivity

Arabidopsis thaliana

Immunogen

Recombinant Arabidopsis thaliana SSRP1 protein

Immunogen Species

Arabidopsis thaliana (Mouse-ear cress)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Target Background

Function

Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II. Binds specifically to double-stranded DNA. Required for karyogamy during female gametophyte development, when the two polar nuclei fuse to form the diploid central cell nucleus.

Gene References into Functions

FACT (SSRP1 and SPT16) is a novel factor required for the accumulation of anthocyanins in response to light-induction. PMID: 29332189
Active DNA demethylation by DEMETER requires SSRP1 function through a distinctly different process from direct DNA methylation control. PMID: 21920319
SPT16 and SSRP1 are critically involved in the regulation of leaf growth, flowering time and seed production, and interact with HUB1/2. PMID: 19947984

Subcellular Location

Nucleus. Chromosome. Note=Colocalizes with RNA polymerase II on chromatin. Recruited to actively transcribed loci.

Protein Families

SSRP1 family

Tissue Specificity

Widely expressed. Present in embryos, shoots and roots, whereas it is not present in terminally differentiated cells such as mature trichoblasts or cells of the root cap (at protein level).

Database Links

KEGG: ath:AT3G28730

STRING: 3702.AT3G28730.1

UniGene: At.21931

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SSRP1 Antibody

Product Details

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Target Background