SST2 Antibody

Datasheet
Code CSB-PA889194XA01SXV
Product Type Polyclonal Antibody
Uniprot No. Q9P371
Delivery Make-to-order
Protocols ELISA Protocol
Immunogen Recombinant Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) SST2 protein
Raised in Rabbit
Species Reactivity Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Tested Applications ELISA, WB (ensure identification of antigen)
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method Protein A/G
Isotype IgG
Clonality Polyclonal
Alias AMSH-like protease sst2 (EC 3.4.19.-) (Suppressor of ste12 deletion protein 2) sst2 SPAC19B12.10
Immunogen Species Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Gene Names sst2
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Zinc metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Does not cleave 'Lys-48'-linked polyubiquitin chains (By similarity). Plays a role in the multivesicular body (MVB) sorting pathway. Required for ubiquitin-dependent sorting of proteins into the endosome and subsequent trafficking to the vacuole. May regulate MVB sorting through deubiquitination of ubiquitinated ESCRT proteins.
Subcellular Location Cytoplasm, Endosome
Protein Families Peptidase M67C family
Database Links

KEGG: spo:SPAC19B12.10

STRING: 4896.SPAC19B12.10.1

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