stam-1 Antibody

Datasheet

Code	CSB-PA022792XA01CXY
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Product Details

Full Product Name

Rabbit anti-Caenorhabditis elegans stam-1 Polyclonal antibody

Uniprot No.

O01498

Target Names

stam-1

Alternative Names

stam-1 antibody; pqn-19 antibody; C34G6.7 antibody; Signal transducing adapter molecule 1 antibody; STAM-1 antibody; Prion-like-(Q/N-rich) domain-bearing protein 19 antibody

Raised in

Rabbit

Species Reactivity

Caenorhabditis elegans

Immunogen

Recombinant Caenorhabditis elegans stam-1 protein

Immunogen Species

Caenorhabditis elegans

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

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Target Background

Function

Binds, sorts and targets the polycystin complex (lov-1 and pkd-2) for lysosomal degradation, acting on early endosomes located at the ciliary base. Functions in the germline together with the ephrin receptor (vab-1) signaling pathway to negatively regulate MAPK activation. May have a role as a positive regulator of meiotic maturation in oocytes, acting independently of vab-1.

Gene References into Functions

These data reveal that the STAM-Hrs complex, which down-regulates ligand-activated growth factor receptors from the cell surface of yeast and mammalian cells, also regulates the localization and signaling of a ciliary PC1 receptor-TRPP2 complex.[STAM] PMID: 17581863

Subcellular Location

Cell projection, cilium. Endosome.

Protein Families

STAM family

Tissue Specificity

Widely expressed, including the pharyngeal intestinal valve, several head neurons, and phasmids in both males and hermaphrodites throughout development. In males, also expressed in the gonad and sensory neurons in the tail. Expressed in the male-specific

Database Links

KEGG: cel:CELE_C34G6.7

STRING: 6239.C34G6.7a.2

UniGene: Cel.7418

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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stam-1 Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background