STN1 Antibody

Code CSB-PA862820XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) STN1 Polyclonal antibody
Uniprot No.
Target Names
STN1
Alternative Names
STN1 antibody; At1g07130 antibody; F10K1.17 antibody; CST complex subunit STN1 antibody; Suppressor of cdc thirteen homolog antibody; AtSTN1 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana STN1 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Component of the CST complex, a complex that binds to single-stranded DNA and is required to protect telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Associates with enzymatically active telomerase. Plays a genomewide role in DNA replication and facilitates re-replication at non-telomeric loci.
Gene References into Functions
  1. STN1 plays a genome-wide role in DNA replication and telomere stability. PMID: 25299252
  2. AtSTN1 is a crucial component of the protective telomere cap in Arabidopsis, and likely in other multicellular eukaryotes. (AtSTN1) PMID: 19064932
  3. CTC1 participates in telomere maintenance in diverse species and that a CST-like complex is required for telomere integrity in multicellular organisms. PMID: 19854131
Subcellular Location
Nucleus. Chromosome, telomere.
Protein Families
STN1 family
Tissue Specificity
Widely expressed.
Database Links

KEGG: ath:AT1G07130

STRING: 3702.AT1G07130.1

UniGene: At.27320

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