Scsalpha1 Antibody

Code CSB-PA839093XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) Scsalpha1 Polyclonal antibody
Uniprot No.
Target Names
Scsalpha1
Alternative Names
Scsalpha1 antibody; Scsalpha antibody; CG1065 antibody; Succinate--CoA ligase [ADP/GDP-forming] subunit alpha antibody; mitochondrial antibody; EC 6.2.1.4 antibody; EC 6.2.1.5 antibody; Succinyl-CoA synthetase subunit alpha antibody; SCS-alpha antibody; Succinyl-coenzyme A synthetase alpha subunit 1 antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) Scsalpha1 protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.
Gene References into Functions
  1. Drosophila SCS deficiency, designated Scsalpha(KO), contained a high level of succinyl-CoA, a substrate for the enzyme, and altered levels of various metabolites in TCA cycle and glycolysis, indicating that the energy metabolism was impaired PMID: 28017724
Subcellular Location
Mitochondrion.
Protein Families
Succinate/malate CoA ligase alpha subunit family
Database Links

KEGG: dme:Dmel_CG1065

STRING: 7227.FBpp0073010

UniGene: Dm.4958

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