SUI1 Antibody

1. Thus, electrostatic interactions involving the eIF1A N-terminal tail stabilize the closed conformation and promote utilization of suboptimal start codons. PMID: 29206102
2. eIF1 Loop 2 interactions with Met-tRNAi control the accuracy of start codon selection by the scanning preinitiation complex. PMID: 29666249
3. The GTPase-activating protein eIF5 and beta-subunit of eIF2 promote transcriptional accuracy by controlling eIF1 dissociation and the stability of ternary complex binding to the preinitiation complex. PMID: 24335188
4. substituting Lys-60 in helix alpha1, or either Lys-37 or Arg-33 in beta-hairpin loop-1, impairs binding of yeast eIF1 to 40 S.eIF1A complexes in vitro, and it confers increased initiation at UUG codons (Sui(-) phenotype) PMID: 23893413
5. Data show that start codon recognition results in a conformational change and release of eIF1 from the ribosome. PMID: 15664195
6. EIF-1 can form the multifactor complex with the ribosome 40S subunit. PMID: 17389391
7. Dissociation of eIF1 from the 40S ribosomal subunit is a key step in start codon selection in vivo. PMID: 17504939

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KEGG: sce:YNL244C

STRING: 4932.YNL244C