smo-1 Antibody

Code CSB-PA345124XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans smo-1 Polyclonal antibody
Uniprot No.
Target Names
smo-1
Alternative Names
smo-1 antibody; smt3 antibody; sumo antibody; K12C11.2 antibody; Small ubiquitin-related modifier antibody; SUMO antibody; Ubiquitin-like protein SMT3 antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans smo-1 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex aos-1-uba-2 and linkage to the E2 enzyme ubc-9, and can be promoted by an E3 ligase such as gei-17. Required for embryonic development, fertility, vulval morphogenesis and inhibition of vulval cell fates. Probably by sumoylating bet-1, prevents muscle myosin depletion in aging adults probably by preventing myoblast growth factor receptor egl-15 overexpression. Plays a role in the attenuation of the let-60/ras pathway. Plays a role in male tail tip morphogenesis. Plays a role in the mitochondrial stress response with its covalent attachment to transcription factors dve-1 and afts-1 negatively regulating the mitochondrial unfolded protein response.
Subcellular Location
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle. Chromosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein Families
Ubiquitin family, SUMO subfamily
Database Links

KEGG: cel:CELE_K12C11.2

STRING: 6239.K12C11.2

UniGene: Cel.18381

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