Su(var)3-7 Antibody

Code CSB-PA324901XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) Su(var)3-7 Polyclonal antibody
Uniprot No.
Target Names
Su(var)3-7
Alternative Names
Su(var)3-7 antibody; Suvar(3)7 antibody; CG8599 antibody; Protein suppressor of variegation 3-7 antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) Su(var)3-7 protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Dose-limiting factor in position-effect variegation, the inactivation in some cells of a gene translocated next to heterochromatin. It could play a role in chromosome condensation.
Gene References into Functions
  1. isolation of three mutations PMID: 12136016
  2. Su(var)3-7 expression is sufficient to induce Su(var)3-9-dependent ectopic heterochromatinisation; there may be a functional link between Su(var)3-7 and the histone-methyltransferase Su(var)3-9 PMID: 15564384
  3. Although structurally very different, Su(var)3-7 and HP1 participate closely in chromocenter and male X polytene chromosome integrity. PMID: 16234327
  4. delineation of functional domains which drive binding to heterochromatin and silencing functions PMID: 16463146
Subcellular Location
Nucleus.
Database Links

KEGG: dme:Dmel_CG8599

STRING: 7227.FBpp0082204

UniGene: Dm.6402

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