SUVH6 Antibody

Code CSB-PA851894XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) SUVH6 Polyclonal antibody
Uniprot No.
Target Names
SUVH6
Alternative Names
SUVH6 antibody; SDG23 antibody; SET23 antibody; At2g22740 antibody; T9I22.18 antibody; Histone-lysine N-methyltransferase antibody; H3 lysine-9 specific SUVH6 antibody; EC 2.1.1.- antibody; Histone H3-K9 methyltransferase 6 antibody; H3-K9-HMTase 6 antibody; Protein SET DOMAIN GROUP 23 antibody; Suppressor of variegation 3-9 homolog protein 6 antibody; Su(var)3-9 homolog protein 6 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana SUVH6 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Histone methyltransferase. Methylates 'Lys-9' of histone H3. H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repression. Seems to act preferentially on dsMRNA.
Gene References into Functions
  1. Data show that H3K9 methyltransferase SUVH6 has a distinct 5-methyl-dC (5mC) base-flipping mechanism involving a thumb loop element. PMID: 30150382
  2. the histone deacetylase HDA6 can interact with the histone methyltransferases SUVH4, SUVH5, and SUVH6 (SUVH4/5/6). PMID: 28778955
  3. This study identified Arabidopsis miR778, a Pi-responsive miRNA, and its target gene Su(var) 3-9 homologs 6 (SUVH6) encoding a histone H3 lysine 9 (H3K9) methyltransferase. PMID: 26259194
  4. H3 lysine 9 methylation is reduced in an suvh4 suvh6 double mutant PMID: 16287862
Subcellular Location
Nucleus. Chromosome, centromere.
Protein Families
Class V-like SAM-binding methyltransferase superfamily, Histone-lysine methyltransferase family, Suvar3-9 subfamily
Database Links

KEGG: ath:AT2G22740

STRING: 3702.AT2G22740.1

UniGene: At.28511

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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