SUVH9 Antibody

Code CSB-PA883019XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) SUVH9 Polyclonal antibody
Uniprot No.
Target Names
SUVH9
Alternative Names
SUVH9 antibody; SDG22 antibody; SET22 antibody; At4g13460 antibody; T6G15.10 antibody; Histone-lysine N-methyltransferase family member SUVH9 antibody; Histone H3-K9 methyltransferase 9 antibody; H3-K9-HMTase 9 antibody; Protein SET DOMAIN GROUP 22 antibody; Suppressor of variegation 3-9 homolog protein 9 antibody; Su(var)3-9 homolog protein 9 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana SUVH9 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Histone methyltransferase family member that plays a role in gene silencing. Together with MORC6 and SUVH2, regulates the silencing of some transposable elements (TEs). According to PubMed:19043555, the protein does not bind S-adenosyl-L-methionine and lacks methyltransferase activity. Instead, it may function downstream of DRM2 in RNA-directed DNA methylation, binding to methylated DNA and recruiting DNA-directed RNA polymerase V to chromatin.
Gene References into Functions
  1. We demonstrate that the SWI/SNF chromatin-remodeling complex components SWI3B, SWI3C, and SWI3D interact with MORC6 as well as with SUVH9 and then mediate transcriptional silencing. These results suggest that the RdDM components are involved not only in DNA methylation but also in MORC6-mediated heterochromatin condensation. PMID: 27171427
  2. SRA-domain proteins (SUVH9) are also essential for DRM2-mediated de novo and maintenance DNA methylation in Arabidopsis thaliana. PMID: 19043555
Subcellular Location
Nucleus. Chromosome, centromere.
Protein Families
Class V-like SAM-binding methyltransferase superfamily, Histone-lysine methyltransferase family, Suvar3-9 subfamily
Database Links

KEGG: ath:AT4G13460

STRING: 3702.AT4G13460.1

UniGene: At.3118

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