swa Antibody

Datasheet

Code	CSB-PA334756XA01DLU
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Target Background

Product Details

Full Product Name

Rabbit anti-Drosophila melanogaster (Fruit fly) swa Polyclonal antibody

Uniprot No.

P40688

Target Names

swa

Alternative Names

swa antibody; CG3429 antibody; Protein swallow antibody

Raised in

Rabbit

Species Reactivity

Drosophila melanogaster (Fruit fly)

Immunogen

Recombinant Drosophila melanogaster (Fruit fly) swa protein

Immunogen Species

Drosophila melanogaster (Fruit fly)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Has a role in localizing bicoid mRNA at the anterior margin of the oocyte during oogenesis, and a poorly characterized role in nuclear divisions in early embryogenesis.

Gene References into Functions

Swa is crucial for the organization of actin networks that lead to the formation of a specialized microtubule population, while Ovhts-RC acts to modulate spatially restricted actin filament growth at the oocyte cortex. PMID: 24677508
Results exclude a role for Swallow in linking bicoid mRNA to the dynein motor. PMID: 20023172
the cytoskeleton in swa mutant oocytes and embryos PMID: 12070614
Recognition of a bicoid mRNA localization signal by a protein complex containing Swallow, Nod, and RNA binding proteins. PMID: 12530962
Molecular characterization of alleles of swallow that may affect swallow function. PMID: 15029497
The weak coiled-coil domain of Drosophila swallow binds tightly to LC8 and becomes significantly more stable in vitro, less susceptible to proteolysis, and more capable of binding other macromolecules in the dynein complex. PMID: 15078108

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Subcellular Location

Nucleus. Note=Uniformly distributed in eggs, becomes localized to the nuclei during early mitotic divisions in early embryogenesis. Enters each nucleus at the beginning of mitosis, occupies a position complementary to that of condensed chromatin, and leaves each nucleus at the end of mitosis.

Database Links

KEGG: dme:Dmel_CG3429

STRING: 7227.FBpp0070884

UniGene: Dm.7242

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Protein Service

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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swa Antibody

Product Details

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Customer Reviews and Q&A

Target Background