SWI1 Antibody

Code CSB-PA362719XA01SVG
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) SWI1 Polyclonal antibody
Uniprot No.
Target Names
SWI1
Alternative Names
SWI1 antibody; ADR6 antibody; GAM3 antibody; YPL016W antibody; LPA1 antibody; SWI/SNF chromatin-remodeling complex subunit SWI1 antibody; Regulatory protein GAM3 antibody; SWI/SNF complex subunit SWI1 antibody; Transcription regulatory protein ADR6 antibody; Transcription regulatory protein SWI1 antibody
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) SWI1 protein
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Involved in transcriptional activation. Component of the SWI/SNF complex, an ATP-dependent chromatin remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors.
Gene References into Functions
  1. NH2-terminal region of approximately 30 amino acids of Swi1 contains all the necessary information for in vivo prion formation, maintenance, and transmission PMID: 28716950
  2. SWI1 overexpression is a Pin+ factor independent of Rnq1; [SWI+] can facilitate [PSI+] conversion but weaken the Pin+ function of [PIN+] PMID: 24727082
  3. Results provide proof of "protein-only" transmission of [SWI(+)] and demonstrate that the widely distributed "dispensable" glutamine/asparagine-rich regions/motifs might have important and divergent biological functions. PMID: 20679490
  4. integrity of S. cerevisiae Swi/Snf complex is required for invasive and filamentous growth promoted by overexpressing CaSwi1 PMID: 19578723
Subcellular Location
Nucleus. Note=While the soluble protein is nuclear, [SWI+] aggregates appear to be cytoplasmic.
Protein Families
SWI1 family
Database Links

KEGG: sce:YPL016W

STRING: 4932.YPL016W

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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